Proton therapy systems are the costliest medical devices in healthcare used for radiation treatment. Proton therapy helps to deliver a beam of protons to disrupt and destroy tumor cells. Proton therapy systems are available in two setup types: single-room setup and multi-room setup. According to the National Association for Proton Therapy (NAPT), single-room proton therapy systems cost around US $40 to US $50 million while multi-room setups may cost up to US$ 200 million.
According to the Particle Therapy Co-Operative Group (PTCOG), by the end of 2023, there were 117 proton therapy centers globally with 46 proton therapy centers in the United States.
Country | Total Proton Therapy Centers |
Austria | 1 |
Belgium | 1 |
China | 6 |
Czech Republic | 1 |
Denmark | 1 |
France | 3 |
Germany | 5 |
India | 1 |
Italy | 4 |
Japan | 19 |
Poland | 1 |
Russia | 5 |
Saudi Arabia | 1 |
Singapore | 3 |
South Korea | 2 |
Spain | 2 |
Sweden | 1 |
Switzerland | 1 |
Thailand | 1 |
Taiwan | 3 |
The Netherlands | 3 |
United Kingdom | 6 |
US | 46 |
Total | 117 |
Manufacturing of proton therapy systems requires intense capital investment and thus there are a limited number of proton therapy system manufacturers.
The top companies of proton therapy systems are given below:
- Varian Medical Systems Inc
- Sumitomo Heavy Industries Ltd
- Hitachi Ltd
- IBA SA
- Mevion Medical Systems
- ProTom International
- Provision Healthcare LLC
- Advanced Oncotherapy Plc
- B dot Medical Inc
- Optivus Proton Therapy Inc
1. Siemens Healthineers (Varian Medical Systems Inc)
Varian Medical Systems is part of Siemens Healthineers which serves more than 70 locations worldwide with approximately 11,000 employees. Varian manufactures proton therapy systems such as ProBeam and ProBeam 360°. ProBeam is available in compact and multi-room setups while ProBeam 360° is available in single rooms, single-room expandable, and multi-room setups.
2. Sumitomo Heavy Industries Ltd
Sumitomo Heavy Industries Ltd manufactures precision machinery, industrial machinery, machinery components, mechatronics, construction machinery, ships, environmental facilities, and plants. Its equipment includes power transmission, waste treatment facilities, pressure vessels, material handling, cryogenic tools, and mobile cranes. Sumitomo operates in more than 180 countries globally. The proton therapy system manufactured by Sumitomo consists of the accelerator (cyclotron), energy selection system, beam transport system, rotating gantry, irradiation nozzle, patient positioning system, etc.
3. Hitachi Ltd
Hitachi, Ltd. provides digital systems and services, green energy and mobility, and connective industry solutions in Japan and internationally. Hitachi offers proton, heavy-ion, and hybrid therapy systems, which can irradiate multiple ion species, so medical institutions can select the best treatment for various types of cancer. In the proton therapy segment, the company offers two main series of products: the PROBEAT series and the Hybrid Particle Therapy System.
4. IBA SA
Ion Beam Applications (IBA) SA is a world leader in particle accelerator technology. IBA has developed proton therapy solutions for more than 60 leading medical centers across the world. IBA has a proton therapy system (ProteusONE) and a unique proton therapy community application in its product portfolio.
5. Mevion Medical Systems Inc.
Mevion Medical Systems, Inc. is a leading provider of proton therapy systems for use in radiation treatment for cancer patients. The product portfolio of Mevion includes MEVION S250-FIT Proton Therapy System, MEVION S250i Proton Therapy System, MEVION S250 Proton Therapy System, and MEVION S250mx Multi-Room Proton Therapy System.
6. ProTom International
ProTom International Holding Corporation is a provider of cost-effective, commercially viable proton therapy systems. The company has U.S. FDA 510 (k) clearance for the system installations. ProTom offers only a single product (Radiance 330 Proton Therapy System) in its product portfolio.
7. Provision Healthcare LLC
Provision Healthcare is a global developer of proton therapy treatment centers and a leader in innovative technology solutions. The company offers ProNova SC360 (The first and only superconducting compact 360˚proton therapy system.)
8. Advanced Oncotherapy Plc
Advanced Oncotherapy plc is a UK-based firm that provides an economical proton-based radiation option known as LIGHT. The LIGHT system, based on groundbreaking technology developed and tested at the world-renowned CERN in Switzerland, provides an integrated proton radiation system for cancer treatment.
9. B dot Medical Inc
B dot Medical Inc. is a private company in Japan. The company has more than 50 employees. B dot Medical provides consulting support for particle therapy and manufactures Proton therapy systems (under development).
10. Optivus Proton Therapy Inc
Optivus Proton Therapy Inc. offers solutions for the treatment of cancer and non-cancerous diseases. The company offers a single proton therapy system: Conforma 3000 Proton Radiation Treatment System.
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